Measuring Metabolic Engines and Fuels-Seahorse Users Meeting 18.5.17

Agilent Seahorse meeting

Metabolism is the key to understanding cell function

In living cells, most of the energy produced is derived from three fuel sources: glucose, glutamine, and fatty acids. Mitochondrial access to these fuels impacts a wide variety of biological processes.

Use the Agilent Seahorse XF Analyzer to:
• Identify fuel dependencies to uncover cancer cell vulnerabilities.
• Explore how fuel preferences lead to cell fate decisions for differentiation and immune cell activation.
• Determine whether/how cells can adjust fuel oxidation to match nutrient availability while meeting energy demand.
• Distinguish metabolic adaptations due to genetic changes vs. those that take place due to nutrient deprivation.

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Agenda

08:30-09:00 Coffee and welcome
09:00-09:15 Opening
Dr. Elena Ainbinder, Head of Stem Cell Core and Advanced Cell Technologies Unit
Dept. of Life Sciences Core Facilities, Weizmann Institute of Science
09:15–09:45 Discovering Bioenergetic Anticancer Targets in vitro
Prof. Richard K. Porter, Head of Biochemistry School of Biochemistry & Immunology, Trinity College Dublin, Ireland.
09:45–10:15 The onco-metabolic role and liabilities of the TCA cycle in cancer
Prof. Eyal Gottlieb, Laura and Isaac Perlmutter National Metabolomics Center, TICC, Technion
10:15–10:45 The world’s most powerful metabolic analyzers and assays
Dr. Svetoslav Kalaydjiev
, Agilent Technologies, Inc.
10:45–11:15 Coffee break
11:15–11:45 The workflow involved in deciphering mitochondrial dysfunction
Prof. Orian Shirihai, Department of Clinical Biochemistry and Pharmacology Faculty of Health Sciences, Ben-Gurion University
11:45–12:15 MTCH2: A new regulator of mitochondria function in homeostasis and stress
Prof. Atan Gross, Department of Biological Regulation, Weizmann Institute of Science
12:15–12:45 Circadian control of mitochondrial function
Dr. Gad Asher
, Department of Biological Chemistry, Weizmann Institute of Science
12:45–14:00 Lunch
14:00-14:15 Investigation of changes in metabolism during spermatogenesis
Dr. Nina Mayorek, Prof. Eli Pikarsky lab, Immunology and Cancer Research, Medical School, Hebrew Universityof Jerusalem
14:15-14:30 eIF2B links translational control to mitochondrial aerobic respiration in VWM disease
Melisa Herrero, Prof Orna Elroy-Stein Lab, Department of Cell Research and Immunology, Faculty of Life Sciences, Tel Aviv University
14:30-14:45 Seahorse: Artifacts and Other Mysteries
A.O. Saragov, Dr. Michael Berger Lab, Department of Immunology and Cancer Research, Hebrew University Medical School

 

Participating in the meeting is free of charge, however advance registration is required.
The number of participants is limited.

Click to register

For information please contact doritm@eldan.biz 

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